Capque Sign Compliance Library

Practical, role-targeted guides on building and choosing electronic signatures that survive an FDA or EMA, written for the people who own the risk.

For Clinical, Regulatory & Executive Teams

21 CFR Part 11-Compliant Electronic Signatures for Clinical Trials

The complete guide to Part 11 & Annex 11 e-signatures — what regulators require and how to evaluate a system built for trials.

🕑 10 min readRead →
For Biotech Founders & CEOs

The Board-Level Risk of Non-Compliant E-Signatures in Clinical Trials

A signature failure can cost a milestone, a partnership, or the trial. Why this is a CEO problem, not just a QA one.

🕑 7 min readRead →
For Clinical Operations Leaders

How Clinical Operations Leaders Cut Signature Cycle Time Without Losing Compliance

The bottleneck was never signing — it was chasing, version confusion, and reconciliation. Reduce the tax, keep the controls.

🕑 8 min readRead →
For Regulatory Affairs & QA Directors

The E-Signature Audit-Readiness Checklist Every QA Director Needs

A control-by-control checklist to confirm your e-signatures are defensible — before an inspector tests them for you.

🕑 9 min readRead →
For Sponsors & CROs

Multi-Site Signature Governance for Sponsors and CROs

One trial is a workflow problem; a portfolio is a governance problem. Standardize signatures without slowing sites.

🕑 8 min readRead →
For Clinical Data Management & eTMF

Keeping Every Signature Audit-Ready in Your eTMF

A signed file in an inbox isn't a record — it's a reconciliation task waiting to become a finding. Keep signatures tied to the record.

🕑 8 min readRead →

Not sure your signatures would survive an audit?

Book a discovery call and we’ll walk your signing workflow against the Part 11 and Annex 11 controls that matter.

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